Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(2-amino-3-pyrimidin-2-ylpyrazolo[1,5-a]pyrimidin-5-yl)-2-[(1S)-1-cyclopropylethyl]-7-(trifluoromethyl)-3H-isoindol-1-one
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Canonical SMILES
C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)C(F)(F)F)-c1ccn2nc(N)c(-c3ncccn3)c2n1
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Compound Formula C24H20F3N7O
Compound Structure
Protein Name
 Protein Info 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P48736
Gene Name
PIK3CG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 53 nM
   TI
   LI
   LO
   TS
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 800 nM
   TI
   LI
   LO
   TS