Brief Information of the Compound and Protein
Compound Name
2-[(1S)-1-cyclopropylethyl]-7-methyl-5-[3-(1-methylpyrazol-4-yl)imidazo[1,2-b]pyridazin-6-yl]-3H-isoindol-1-one
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Canonical SMILES
C[C@@H](C1CC1)N1Cc2cc(cc(C)c2C1=O)-c1ccc2ncc(-c3cnn(C)c3)n2n1
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Compound Formula C24H24N6O
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P48736
Gene Name
PIK3CG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 440 nM
   TI
   LI
   LO
   TS