Brief Information of the Compound and Protein
Compound Name
(R)-4-(2-(1-Methyl-1H-pyrazol-5-yl)-4-(trifluoromethyl)phenyl)-N-(pyrimidin-2-yl) chromane-7-sulfonamide
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PubChem ID
CID: 126668795
Canonical SMILES
Cn1nccc1-c1cc(ccc1[C@H]1CCOc2cc(ccc12)S(=O)(=O)Nc1ncccn1)C(F)(F)F
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Compound Formula C24H20F3N5O3S
Compound Structure
Protein Name
Sodium channel protein type 9 subunit alpha
Protein Classification
Ion channel
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Voltage-gated ion channel
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Voltage-gated sodium channel
Uniprot ID
Q15858
Gene Name
SCN9A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  5
1
IC50 = 15.9 nM
   TI
   LI
   LO
   TS
2
IC50 = 17.8 nM
   TI
   LI
   LO
   TS
3
IC50 = 29.8 nM
   TI
   LI
   LO
   TS
4
IC50 = 45.3 nM
   TI
   LI
   LO
   TS
5
IC50 = 9500 nM
   TI
   LI
   LO
   TS