Brief Information of the Compound and Protein
Compound Name
4-methyl-3-[4-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine
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PubChem ID
CID: 156019904
Canonical SMILES
COc1cc(cc(OC)c1OC)-c1cncc(c1C)-c1ccc(cc1)C1=CCN(C)CC1
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Compound Formula C27H30N2O3
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 7803 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2520 nM