Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(5-fluoropyridin-2-yl)-2-[[(2S)-3-[5-methyl-2-(triazol-2-yl)benzoyl]-1,3-oxazinan-2-yl]methyl]-1,2,4-triazol-3-one
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 PubChem ID
CID: 150278464
Canonical SMILES
Cc1ccc(c(c1)C(=O)N1CCCO[C@H]1Cn1ncn(-c2ccc(F)cn2)c1=O)-n1nccn1
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Compound Formula C22H21FN8O3
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 85.5 nM
   TI
   LI
   LO
   TS