Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[(2S)-2-[[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]methyl]-1,3-oxazinan-3-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
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 PubChem ID
CID: 137419776
Canonical SMILES
Cc1ccc(c(c1)C(=O)N1CCCO[C@H]1Cn1ccc(n1)-c1ccc(F)cn1)-n1nccn1
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Compound Formula C23H22FN7O2
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1.27 nM
   TI
   LI
   LO
   TS