Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10080744, Example 18
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 PubChem ID
CID: 121302281
Canonical SMILES
C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2cnc(CC(C)(C)C(O)=O)s2)c(Cl)c1Cl)C(F)(F)F
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Compound Formula C25H26Cl2F3N3O4S3
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-beta
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
Uniprot ID
Q92753
Gene Name
RORB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 148 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 474 nM