Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[2,3-dichloro-4-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]phenyl]-N,N-diethyl-2-[5-(2-hydroxypropan-2-yl)-1,3,4-oxadiazol-2-yl]-1,3-thiazole-4-carboxamide
    Show/Hide
 PubChem ID
CID: 121303961
Canonical SMILES
CCN(CC)C(=O)c1nc(sc1-c1ccc(c(Cl)c1Cl)S(=O)(=O)N[C@@H](C)C(F)(F)F)-c1nnc(o1)C(C)(C)O
    Show/Hide
Compound Formula C22H24Cl2F3N5O5S2
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group F
>
Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 5 nM