Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[5-[2-chloro-4-[[(2S)-1,1,1-trifluorobutan-2-yl]sulfamoyl]phenyl]-4-(cyclobutylmethyl)-1,3-thiazol-2-yl]-2,2-dimethylpropanoic acid
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 PubChem ID
CID: 156021975
Canonical SMILES
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(CC(C)(C)C(O)=O)nc2CC2CCC2)c(Cl)c1)C(F)(F)F
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Compound Formula C23H28ClF3N2O4S2
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 15.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 6.5 nM