Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-((R)-1-((1s,4S)-4-(3,3-difluoroazetidin-1-yl)cyclohexyl)ethyl)-2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1H-indole-3-carboxamide
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Canonical SMILES
CSc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)[C@H]2CC[C@@H](N3CC(F)(F)C3)CC2)c2ccccc12
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Compound Formula C29H36F2N4O2S
Compound Structure
Protein Name
 Protein Info 
Histone-lysine N-methyltransferase EZH2
Protein Classification
Epigenetic regulator
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Protein methyltransferase
Uniprot ID
Q15910
Gene Name
EZH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 5.9 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 0.18 nM
   TI
   LI
   LO
   TS