Brief Information of the Compound and Protein
Compound Name
6-(3,5-dichloro-4-hydroxyphenyl)-4-[[4-[(dimethylamino)methyl]cyclohexyl]amino]-N-(2-methylpropyl)-1,5-naphthyridine-3-carboxamide
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Canonical SMILES
CC(C)CNC(=O)c1cnc2ccc(nc2c1N[C@H]1CC[C@H](CN(C)C)CC1)-c1cc(Cl)c(O)c(Cl)c1
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Compound Formula C28H35Cl2N5O2
Compound Structure
Protein Name
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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CMGC protein kinase group
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CMGC protein kinase DYRK family
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CMGC protein kinase Dyrk1 subfamily
Uniprot ID
Q13627
Gene Name
DYRK1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 6 nM
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