Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol]
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 PubChem ID
CID: 3689
SID: 14752941
Canonical SMILES
CC(C(O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1
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Compound Formula C21H27NO2
Compound Structure
Protein Name
 Protein Info 
Glutamate receptor ionotropic, NMDA 2B
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Ionotropic glutamate receptor
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NMDA receptor
Uniprot ID
Q13224
Gene Name
GRIN2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000101 L-M(TK-)
 Cell Line Info 
Mus musculus (Mouse)  3
1
IC50 = 13.3 nM
   TI
   LI
   LO
   TS
2
Ki = 10 nM
   TI
   LI
   LO
   TS
3
Ki = 10.07 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM