Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4R,5R)-5-(4-Fluorophenyl)-4-(5-((5-fluoropyridin-3-yl)ethynyl)pyridin-3-yl)oxazolidin-2-one
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 PubChem ID
CID: 69084420
Canonical SMILES
O=C1N[C@H](c2cncc(C#Cc3cncc(F)c3)c2)[C@@H](c2ccc(F)cc2)O1
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Compound Formula C21H13F2N3O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 6 nM
   TI
   LI
   LO
   TS
2
EC50 = 315 nM
   TI
   LI
   LO
   TS
3
Ki = 25 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 25 nM