Brief Information of the Compound and Protein
Compound Name
(4R,5R)-5-phenyl-4-[5-(2-phenylethynyl)pyridin-3-yl]-1,3-oxazolidin-2-one
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PubChem ID
CID: 69092896
Canonical SMILES
O=C1N[C@@H]([C@H](O1)c1ccccc1)c1cncc(c1)C#Cc1ccccc1
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Compound Formula C22H16N2O2
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
EC50 = 0.7 nM
   TI
   LI
   LO
   TS
2
EC50 > 3000 nM
   TI
   LI
   LO
   TS
3
Ki = 1.4 nM
   TI
   LI
   LO
   TS