Brief Information of the Compound and Protein
Compound Name
3-[3-[4-(1-aminocyclobutyl)phenyl]-5-(3-aminophenyl)imidazo[4,5-b]pyridin-2-yl]pyridin-2-amine;hydrochloride
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PubChem ID
CID: 155563831
Canonical SMILES
Cl.Nc1cccc(c1)-c1ccc2nc(-c3cccnc3N)n(-c3ccc(cc3)C3(N)CCC3)c2n1
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Compound Formula C27H26ClN7
Compound Structure
Protein Name
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 1.9 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.6 nM
   TI
   LI
   LO
   TS