Brief Information of the Compound and Protein
Compound Name
2-methoxyethyl 2-{4-[(1R)-1-({4,5-dichloro-1,6-dimethyl-1H-pyrrolo[2,3- b]pyridin-2-yl}formamido)ethyl]benzenesulfonyl}acetate
    Show/Hide
PubChem ID
CID: 142427650
Canonical SMILES
COCCOC(=O)CS(=O)(=O)c1ccc(cc1)[C@@H](C)NC(=O)c1cc2c(Cl)c(Cl)c(C)nc2n1C
    Show/Hide
Compound Formula C23H25Cl2N3O6S
Compound Structure
Protein Name
D-3-phosphoglycerate dehydrogenase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
O43175
Gene Name
PHGDH
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000196 MDA-MB-468 Homo sapiens (Human)  1
1
IC50 = 82.8 nM
   TI
   LI
   LO
   TS