Brief Information of the Compound and Protein
Compound Name
2-(2-bromo-3-fluoro-4-hydroxy-5-((2-(pyridin-2-ylmethylamino)pyrimidin-5-yl)methoxy)benzylidene)thieno[2,3-b]pyridin-3(2H)-one
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PubChem ID
CID: 140897153
Canonical SMILES
O=C1/C(=C/c2cc(OCc3cnc(NCc4ccccn4)nc3)c(O)c(F)c2Br)Sc2ncccc21
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Compound Formula C25H17BrFN5O3S
Compound Structure
Protein Name
Cyclic GMP-AMP synthase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8N884
Gene Name
CGAS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 >= 10000 nM
   TI
   LI
   LO
   TS