Brief Information of the Compound and Protein
Compound Name
2-(5-(1-(2-aminopyrimidin-5-yl)ethoxy)-2-bromo-3-fluoro-4-hydroxybenzylidene)-5-fluorothieno[2,3-b]pyridin-3(2H)-one
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PubChem ID
CID: 140897212
Canonical SMILES
CC(Oc1cc(/C=C2\Sc3ncc(F)cc3C2=O)c(Br)c(F)c1O)c1cnc(N)nc1
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Compound Formula C20H13BrF2N4O3S
Compound Structure
Protein Name
Cyclic GMP-AMP synthase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8N884
Gene Name
CGAS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 2500 nM
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