Brief Information of the Compound and Protein
Compound Name
(S)-5-(4-((2,4-difluorophenyl)fluoromethyl)piperidin-1-yl)-6-(isopropylamino)pyrazine-2-carbonitrile
    Show/Hide
PubChem ID
CID: 118319047
Canonical SMILES
CC(C)Nc1nc(cnc1N1CCC(CC1)[C@H](F)c1ccc(F)cc1F)C#N
    Show/Hide
Compound Formula C20H22F3N5
Compound Structure
Protein Name
G-protein coupled receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
Uniprot ID
P46095
Gene Name
GPR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 30200 nM
   TI
   LI
   LO
   TS