Brief Information of the Compound and Protein
Compound Name
N-[(5-chloro-2-propoxyphenyl)methyl]-2-(1H-imidazol-5-yl)-N-[2-[4-(prop-2-ynylsulfamoyl)phenyl]ethyl]acetamide
    Show/Hide
PubChem ID
CID: 155525529
Canonical SMILES
CCCOc1ccc(Cl)cc1CN(CCc1ccc(cc1)S(=O)(=O)NCC#C)C(=O)Cc1c[nH]cn1
    Show/Hide
Compound Formula C26H29ClN4O4S
Compound Structure
Protein Name
NACHT, LRR and PYD domains-containing protein 3
Protein Classification
Unclassified protein
Uniprot ID
Q8R4B8
Gene Name
NLRP3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000188 J774A1 Mus musculus (Mouse)  1
1
IC50 = 1660 nM
   TI
   LI
   LO
   TS