Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9447106, 27b (peak 2)
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 PubChem ID
CID: 135565884
Canonical SMILES
NC(=O)c1c2NCC[C@@H](C3CCN(CC3)C(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1
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Compound Formula C27H29N5O3
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase Tec
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
P42680
Gene Name
TEC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 204.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2 nM
2 IC50 = 44 nM
3 IC50 = 204.7 nM
4 Kd = 18 nM