Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea
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 PubChem ID
CID: 60490
SID: 12014274
Canonical SMILES
CC(N(O)C(N)=O)c1cc2ccccc2s1
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Compound Formula C11H12N2O2S
Compound Structure
Protein Name
 Protein Info 
Polyunsaturated fatty acid 5-lipoxygenase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P09917
Gene Name
ALOX5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000831 PMNL
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 521 nM
   TI
   LI
   LO
   TS
2
IC50 = 2310 nM
   TI
   LI
   LO
   TS
3
IC50 = 2500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 100 nM
2 IC50 = 150 nM
3 IC50 = 300 nM
4 IC50 = 350 nM
5 IC50 = 410 nM
6 IC50 = 500 nM
7 IC50 = 518 nM
8 IC50 = 540 nM
9 IC50 = 560 nM
10 IC50 = 590 nM
11 IC50 = 600 nM
12 IC50 = 660 nM
13 IC50 = 800 nM
14 IC50 = 1000 nM
15 IC50 = 1100 nM
16 IC50 = 1700 nM
17 IC50 = 1800 nM
18 IC50 = 2000 nM
19 IC50 = 2200 nM
20 IC50 = 3000 nM
21 IC50 = 3300 nM
22 IC50 = 3500 nM
23 IC50 = 3700 nM
24 IC50 = 5300 nM
25 IC50 = 6300 nM