Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2,6-dimethoxy-4-[4-methyl-5-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pyridin-3-yl]benzamide
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 PubChem ID
CID: 155532969
Canonical SMILES
COc1cc(cc(OC)c1C(N)=O)-c1cncc(-c2ccc(cc2)N2CCN(CC2)C(C)C)c1C
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Compound Formula C28H34N4O3
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 276 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 66 nM