Brief Information of the Compound and Protein
Compound Name
9-(4-hydroxycyclohexyl)-2-(4-methoxy-2-methylanilino)-7-methylpurin-8-one
    Show/Hide
Canonical SMILES
COc1ccc(Nc2ncc3n(C)c(=O)n([C@H]4CC[C@H](O)CC4)c3n2)c(C)c1
    Show/Hide
Compound Formula C20H25N5O3
Compound Structure
Protein Name
DNA-dependent protein kinase catalytic subunit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
Uniprot ID
P78527
Gene Name
PRKDC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 31.62 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 0.3162 nM
   TI
   LI
   LO
   TS