Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-methyl-6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-7-[[(1S)-2-methyl-1-pyridin-2-ylpropyl]amino]-4H-pyrazolo[4,3-b]pyridin-5-one
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 PubChem ID
CID: 138661878
Canonical SMILES
CC(C)[C@H](Nc1c(-c2nc3ccc(cc3[nH]2)N2CCN(C)CC2)c(=O)[nH]c2cn(C)nc12)c1ccccn1
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Compound Formula C28H33N9O
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 26.66 nM
   TI
   LI
   LO
   TS
2
IC50 = 29.14 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.2885 nM
2 IC50 = 1.061 nM