Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-methyl-6-[5-morpholin-4-yl-6-(trifluoromethyl)-1H-benzimidazol-2-yl]-7-[[(1R)-1-(1,3-oxazol-4-yl)ethyl]amino]-4H-pyrazolo[4,3-b]pyridin-5-one
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 PubChem ID
CID: 138661862
Canonical SMILES
C[C@@H](Nc1c(-c2nc3cc(c(cc3[nH]2)N2CCOCC2)C(F)(F)F)c(=O)[nH]c2cn(C)nc12)c1cocn1
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Compound Formula C24H23F3N8O3
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
2
IC50 = 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 254.3 nM
2 IC50 = 933.4 nM