Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-methyl-6-(6-morpholin-4-yl-3H-imidazo[4,5-c]pyridin-2-yl)-7-[[(1S)-1-pyrimidin-2-ylethyl]amino]-4H-pyrazolo[4,3-b]pyridin-5-one
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 PubChem ID
CID: 138662575
Canonical SMILES
C[C@H](Nc1c(-c2nc3cnc(cc3[nH]2)N2CCOCC2)c(=O)[nH]c2cn(C)nc12)c1ncccn1
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Compound Formula C23H24N10O2
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 5.896 nM
   TI
   LI
   LO
   TS
2
IC50 = 9.538 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.212 nM
2 IC50 = 0.4113 nM