Brief Information of the Compound and Protein
Compound Name
5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
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PubChem ID
CID: 135398744
SID: 14883184
Canonical SMILES
CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1
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Compound Formula C22H30N6O4S
Compound Structure
Protein Name
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 8
>
Phosphodiesterase 8A
Uniprot ID
O60658
Gene Name
PDE8A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 100000 nM
2 IC50 > 10000 nM