Brief Information of the Compound and Protein
Compound Name
(2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11(16),12,14-tetraene-4,7-dione
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PubChem ID
CID: 110635
SID: 14756405
Canonical SMILES
CN1CC(=O)N2[C@H](Cc3c([nH]c4ccccc34)[C@H]2c2ccc3OCOc3c2)C1=O
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Compound Formula C22H19N3O4
Compound Structure
Protein Name
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 6
>
Phosphodiesterase 6C
Uniprot ID
P51160
Gene Name
PDE6C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 402 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS