Brief Information of the Compound and Protein
Compound Name
N-(2-methylcyclohexyl)-1-[5-[5-[2-(5-methylpyridin-2-yl)ethyl]pyrazol-1-yl]-1,3,4-thiadiazol-2-yl]piperidine-4-carboxamide
    Show/Hide
PubChem ID
CID: 155512546
Canonical SMILES
CC1CCCCC1NC(=O)C1CCN(CC1)c1nnc(s1)-n1nccc1CCc1ccc(C)cn1
    Show/Hide
Compound Formula C26H35N7OS
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
>
Frizzled family G protein-coupled receptor
>
Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 57 nM
   TI
   LI
   LO
   TS