Brief Information of the Compound and Protein
Compound Name
2-[5-[(2R)-4-(5-benzyl-1,3,4-thiadiazol-2-yl)-2-methylpiperazin-1-yl]pyrazin-2-yl]propan-2-ol
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PubChem ID
CID: 155525583
Canonical SMILES
C[C@@H]1CN(CCN1c1cnc(cn1)C(C)(C)O)c1nnc(Cc2ccccc2)s1
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Compound Formula C21H26N6OS
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 > 10000 nM
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