Brief Information of the Compound and Protein
Compound Name
4-fluoro-N-methyl-N-[1-[5-(2-methylpyrazol-3-yl)-1,3,4-thiadiazol-2-yl]piperidin-4-yl]-2-(trifluoromethyl)benzamide
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PubChem ID
CID: 155553830
Canonical SMILES
CN(C1CCN(CC1)c1nnc(s1)-c1ccnn1C)C(=O)c1ccc(F)cc1C(F)(F)F
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Compound Formula C20H20F4N6OS
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS