Brief Information of the Compound and Protein
Compound Name
N-(2-methylcyclohexyl)-1-[5-[5-[(5-methylpyridin-2-yl)oxymethyl]pyrazol-1-yl]-1,3,4-thiadiazol-2-yl]piperidine-4-carboxamide
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PubChem ID
CID: 155517391
Canonical SMILES
CC1CCCCC1NC(=O)C1CCN(CC1)c1nnc(s1)-n1nccc1COc1ccc(C)cn1
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Compound Formula C25H33N7O2S
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 42 nM
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