Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-N-[(1R,2R,5R,6R,14S)-6-[benzenesulfonyl(cyclopropylmethyl)amino]-11-methoxy-15-oxatetracyclo[10.2.1.05,14.08,13]pentadeca-8(13),9,11-trien-2-yl]-3-(furan-3-yl)-N-methylprop-2-enamide
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 PubChem ID
CID: 155557825
Canonical SMILES
COc1ccc2C[C@H]([C@@H]3CC[C@H]([C@@H]4Oc1c2[C@H]34)N(C)C(=O)\C=C\c1ccoc1)N(CC1CC1)S(=O)(=O)c1ccccc1
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Compound Formula C33H36N2O6S
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 20.9 nM
   TI
   LI
   LO
   TS