Brief Information of the Compound and Protein
Compound Name
(2R,3R)-3-cyclopropyl-3-[3-[[4-(2-fluoro-5-methoxyphenyl)cyclohexyl]methoxy]phenyl]-2-methylpropanoic acid
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Canonical SMILES
COc1ccc(F)c(c1)[C@H]1CC[C@H](COc2cccc(c2)[C@@H]([C@@H](C)C(O)=O)C2CC2)CC1
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Compound Formula C27H33FO4
Compound Structure
Protein Name
Free fatty acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 22 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 2.2 nM
   TI
   LI
   LO
   TS