Brief Information of the Compound and Protein
Compound Name
3-chloro-4-[(3R,4S)-4-(4-chlorophenyl)sulfonyl-3-hydroxy-3-(hydroxymethyl)pyrrolidin-1-yl]sulfonylbenzonitrile
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PubChem ID
CID: 134374895
Canonical SMILES
OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(cc1Cl)C#N
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Compound Formula C18H16Cl2N2O6S2
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 4
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q9HBA0
Gene Name
TRPV4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000932 BHK/AC9 Mesocricetus auratus (Golden hamster)  1
1
IC50 = 3.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.2 nM