Brief Information of the Compound and Protein
Compound Name
 Compound Info 
JNJ-26481585
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 PubChem ID
CID: 11538455
SID: 16640562
Canonical SMILES
Cn1cc(CNCC2CCN(CC2)c2ncc(cn2)C(=O)NO)c2ccccc12
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Compound Formula C21H26N6O2
Compound Structure
Protein Name
 Protein Info 
Histone deacetylase 1
Protein Classification
Epigenetic regulator
>
Eraser
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Histone deacetylase
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HDAC class I
Uniprot ID
Q13547
Gene Name
HDAC1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 0.11 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.617 nM
   TI
   LI
   LO
   TS
3
IC50 = 0.62 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.11 nM
2 IC50 = 1.7 nM
3 IC50 = 4.26 nM
4 Ki = 0.03 nM
5 Ki = 0.48 nM
6 Ki = 7.3 nM