Brief Information of the Compound and Protein
Compound Name
4-[[4-[(4-hydroxycyclohexyl)methylamino]-1-adamantyl]methylamino]-2-[(2-methylsulfanylphenyl)methylamino]pyrimidine-5-carbonitrile
    Show/Hide
Canonical SMILES
CSc1ccccc1CNc1ncc(C#N)c(NCC23CC4CC(C2)C(NC[C@H]2CC[C@H](O)CC2)C(C4)C3)n1
    Show/Hide
Compound Formula C31H42N6OS
Compound Structure
Protein Name
Protein kinase C theta type
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase PKC family
>
AGC protein kinase PKC delta subfamily
Uniprot ID
Q04759
Gene Name
PRKCQ
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.94 nM