Brief Information of the Compound and Protein
Compound Name
(E)-3-[4-[(6S,8R)-7-(2,2-difluoropropyl)-6,8-dimethyl-8,9-dihydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl]-3,5-difluorophenyl]prop-2-enoic acid
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PubChem ID
CID: 155511936
Canonical SMILES
C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@](C)(N1CC(C)(F)F)c1c(F)cc(\C=C\C(O)=O)cc1F
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Compound Formula C24H23F4N3O2
Compound Structure
Protein Name
Estrogen receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7 Homo sapiens (Human)  1
1
IC50 = 0.7943 nM
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