Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-3-[4-[(1R)-6-hydroxy-2-(2-methylpropyl)-3,4-dihydro-1H-isoquinolin-1-yl]phenyl]prop-2-enoic acid
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 PubChem ID
CID: 127030545
Canonical SMILES
CC(C)CN1CCc2cc(O)ccc2[C@H]1c1ccc(\C=C\C(O)=O)cc1
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Compound Formula C22H25NO3
Compound Structure
Protein Name
 Protein Info 
Estrogen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
>
Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 3.981 nM
   TI
   LI
   LO
   TS
2
IC50 = 4.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 26 nM