Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[2-[6-[3-(difluoromethoxy)-5-fluorophenyl]-1-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydroindol-2-yl]acetyl]azetidine-3-carboxylic acid
    Show/Hide
 PubChem ID
CID: 155567816
Canonical SMILES
OC(=O)C1CN(C1)C(=O)CC1Cc2ccc(cc2N1S(=O)(=O)c1cccc(c1)C(F)(F)F)-c1cc(F)cc(OC(F)F)c1
    Show/Hide
Compound Formula C28H22F6N2O6S
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group F
>
Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 4050 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 49.3 nM