Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[6-[3-(difluoromethoxy)-5-fluorophenyl]-1-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydroindol-2-yl]-1-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethanone
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 PubChem ID
CID: 155523503
Canonical SMILES
FC(F)Oc1cc(F)cc(c1)-c1ccc2CC(CC(=O)N3CC4(COC4)C3)N(c2c1)S(=O)(=O)c1cccc(c1)C(F)(F)F
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Compound Formula C29H24F6N2O5S
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 752 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 47.9 nM