Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-3-[4-[[5-amino-3-(4-sulfamoylanilino)-1,2,4-triazole-1-carbonyl]amino]phenyl]prop-2-enoic acid
    Show/Hide
 PubChem ID
CID: 155538703
Canonical SMILES
Nc1nc(Nc2ccc(cc2)S(N)(=O)=O)nn1C(=O)Nc1ccc(\C=C\C(O)=O)cc1
    Show/Hide
Compound Formula C18H17N7O5S
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  4
1
Kd = 180 nM
   TI
   LI
   LO
   TS
2
Kd = 200 nM
   TI
   LI
   LO
   TS
3
Kd = 374 nM
   TI
   LI
   LO
   TS
4
Kd = 6000 nM
   TI
   LI
   LO
   TS