Brief Information of the Compound and Protein
Compound Name
 Compound Info 
Faridak
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 PubChem ID
CID: 6918837
SID: 15274143
Canonical SMILES
Cc1[nH]c2ccccc2c1CCNCc1ccc(\C=C\C(=O)NO)cc1
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Compound Formula C21H23N3O2
Compound Structure
Protein Name
 Protein Info 
Histone deacetylase 1
Protein Classification
Epigenetic regulator
>
Eraser
>
Histone deacetylase
>
HDAC class I
Uniprot ID
Q13547
Gene Name
HDAC1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4
 Cell Line Info 
Trichoplusia ni (Cabbage looper)  1
1
IC50 = 7.03 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2.5 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
2
IC50 = 1.26 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.5 nM
2 IC50 = 1 nM
3 IC50 = 1.4 nM
4 IC50 = 1.778 nM
5 IC50 = 1.809 nM
6 IC50 = 2.123 nM
7 IC50 = 2.143 nM
8 IC50 = 2.5 nM
9 IC50 = 6.8 nM
10 IC50 < 15 nM
11 IC50 = 15 nM
12 IC50 = 20 nM
13 IC50 = 26 nM
14 IC50 < 300 nM
15 Ki = 0.54 nM
16 Ki = 1 nM
17 Ki = 2.5 nM
18 Ki = 3 nM