Brief Information of the Compound and Protein
Compound Name
(2R)-9-[2-(2-fluorophenyl)ethyl]-2-methyl-4-[4-(trifluoromethyl)pyridin-3-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
    Show/Hide
PubChem ID
CID: 126744972
Canonical SMILES
C[C@H]1OC2(CCN(CCc3ccccc3F)CC2)CN(C1=O)c1cnccc1C(F)(F)F
    Show/Hide
Compound Formula C23H25F4N3O2
Compound Structure
Protein Name
Sigma non-opioid intracellular receptor 1
Protein Classification
Membrane receptor
Uniprot ID
Q99720
Gene Name
SIGMAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 61 nM
   TI
   LI
   LO
   TS