Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[1-(2,6-dichlorobenzoyl)indazol-3-yl]benzoic acid
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 PubChem ID
CID: 60162553
SID: 144110067
Canonical SMILES
OC(=O)c1ccc(cc1)-c1nn(C(=O)c2c(Cl)cccc2Cl)c2ccccc12
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Compound Formula C21H12Cl2N2O3
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
2
IC50 = 400 nM
   TI
   LI
   LO
   TS
CL000789 HG5LN
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2 nM