Brief Information of the Compound and Protein
Compound Name
6-methyl-N-[7-methyl-8-[(2S,4R)-2-methyl-1-[4,4,4-trifluoro-3-(trifluoromethyl)butanoyl]piperidin-4-yl]oxy-[1,2,4]triazolo[1,5-a]pyridin-6-yl]pyridine-3-carboxamide
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PubChem ID
CID: 155553079
Canonical SMILES
C[C@H]1C[C@@H](CCN1C(=O)CC(C(F)(F)F)C(F)(F)F)Oc1c(C)c(NC(=O)c2ccc(C)nc2)cn2ncnc12
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Compound Formula C25H26F6N6O3
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 1500 nM
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