Brief Information of the Compound and Protein
Compound Name
N-[8-[[(3S)-4-(cyclopentanecarbonyl)-3-methylpiperazin-1-yl]methyl]-7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-6-methylpyridine-3-carboxamide
    Show/Hide
PubChem ID
CID: 155563358
Canonical SMILES
C[C@H]1CN(Cc2c(C)c(NC(=O)c3ccc(C)nc3)cn3ncnc23)CCN1C(=O)C1CCCC1
    Show/Hide
Compound Formula C26H33N7O2
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group F
>
Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS