Brief Information of the Compound and Protein
Compound Name
(4S)-3'-(3,6-dihydro-2H-pyran-5-yl)-1'-fluoro-7'-(2-fluoropyridin-3-yl)spiro[5H-1,3-oxazole-4,5'-chromeno[2,3-c]pyridine]-2-amine
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PubChem ID
CID: 53465141
SID: 126491269
Canonical SMILES
NC1=N[C@@]2(CO1)c1cc(ccc1Oc1c(F)nc(cc21)C1=CCCOC1)-c1cccnc1F
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Compound Formula C24H18F2N4O3
Compound Structure
Protein Name
Beta-secretase 2
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9JL18
Gene Name
BACE2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000396 B16-F1 Mus musculus (Mouse)  1
1
EC50 = 40 nM
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