Brief Information of the Compound and Protein
Compound Name
2,4-difluoro-N-[5-[5-(5-oxo-6,7-dihydropyrrolo[3,4-b]pyridin-3-yl)thiophen-2-yl]pyridin-3-yl]benzenesulfonamide
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PubChem ID
CID: 155531182
Canonical SMILES
Fc1ccc(c(F)c1)S(=O)(=O)Nc1cncc(c1)-c1ccc(s1)-c1cnc2CNC(=O)c2c1
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Compound Formula C22H14F2N4O3S2
Compound Structure
Protein Name
Perforin-1
Protein Classification
Ion channel
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Other ion channel
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Pore-forming toxins (proteins and peptides)
Uniprot ID
P14222
Gene Name
PRF1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CL000975 KHYG-1 Homo sapiens (Human)  1
1
IC50 = 6800 nM
   TI
   LI
   LO
   TS